CNS（Cell、Nature、Science）三大顶级期刊是全球基础研究水平的重要风向标，其发文结构体现了国际科研力量格局与前沿方向的演进。本文基于Web of Science与InCites平台，对2015~2024年CNS发表的Article论文进行统计分析，从发文国别、科研城市、学科结构、研究热点、国际合作以及作者特征等维度刻画全球基础研究趋势。结果显示：美国仍保持主导地位，但占比呈下降趋势；中国发文量快速增长，在材料科学、物理学等领域表现突出，但在生命科学、健康相关领域仍存在结构性短板。研究热点呈现向人工智能、病毒学、核酸化学、二维材料等方向聚集的趋势，国际合作规模持续扩大。基于此，本文提出加强原创性研究布局、优化青年科研人才支持体系、提升跨国与跨部门协同能力等政策建议。

CNS journals—Cell, Nature, and Science—serve as key indicators of the global landscape of basic research, with their publication patterns reflecting shifts in international scientific strength and frontier directions. Drawing on data from the Web of Science and InCites platforms, this study analyzes Article publications in CNS journals from 2015 to 2024 across multiple dimensions, including country and city contributions, disciplinary structure, research hotspots, international collaboration, and author characteristics. The results show that the United States maintains its leading position, though its share is declining; China exhibits rapid growth, with strong performance in materials science and physics, but continues to face structural weaknesses in life sciences and health-related fields. Emerging research hotspots are increasingly concentrated in artificial intelligence, virology, nucleic acid chemistry, and two dimensional materials, alongside expanding international collaboration networks. Based on these findings, the study proposes policy recommendations to strengthen original research capabilities, optimize support mechanisms for early-career researchers, and enhance cross-border and cross-sector collaboration.