As an innovation engine for economic and social development, artificial intelligence (AI) is reshaping the industrial landscape and social progress path. Globally, there has been a consensus on active layout in the AI field, aiming to lead future development trends and consolidate international competitive advantages. Taking Changzhou as an example, this paper systematically analyzes the existing foundation and potential for later development of the local AI industry. It proposes an innovative development strategic goal centered on “AI+”, aiming to promote the AIempowered upgrading of local characteristic industries through pathways such as enhancing industrial infrastructure, driving application scenarios, fostering a conducive development environment, and international cooperation. This will inject new impetus into high-quality economic development.