Against the backdrop of digital transformation and industry-education integration, higher vocational colleges are confronted with new development opportunities and challenges. This article analyzes the impact of digital transformation and industry-education integration on the talent cultivation model of higher vocational colleges, and explores the innovative paths of the talent cultivation model of higher vocational colleges to adapt to the development needs of the new era. The results of this discussion provide reference and inspiration for higher vocational colleges to build an industry-education integration teaching system that meets the needs of vocational education.