Driven by the era of digital empowerment education, how to cultivate compound talents with both business thinking and digital literacy is the core direction of breaking through the boundaries of traditional business and building new business, and it is also the objective need for digital economy talents to reconstruct their knowledge system to adapt to social development. Starting from the characteristics of digital economy talents and the knowledge system required, this paper constructs a “four-chain” talent training model and path based on the analysis of the three-dimensional practical dilemmas of students, teachers and schools: interdisciplinary - integration of industry and education - teaching innovation - multi-party collaboration, and finally puts forward relevant policy suggestions such as building a training system with the participation of multiple subjects, strengthening professional construction, deepening the integration of industry and education, and building an information platform.