This study examines the discrepancy between the traditional higher education system and the current demand for talent in regional economic development. It reviews the role of universities in regional growth and emphasizes that application-oriented institutions should strengthen their educational models via industry-university research collaboration, localized technology development, and talent cultivation to better serve local economic needs. By integrating the specific agricultural development requirements of Jilin Province, this paper proposes that local agricultural universities should focus on cultivating versatile talents who possess practical skills, adapt to local conditions, and contribute to technology extension. The study aims to provide a theoretical basis and implementation pathway for synergistic development between talent cultivation and the economy in Jilin Province.