Against the dual background of the comprehensive advancement of industrial digitalization and the restructuring of the global electronic information industry chain, clustering serves as the core organizational form for the high-quality development of the electronic information industry. The co-evolution of the two has become a crucial approach to breaking through bottlenecks in industrial development. At present, China’s electronic information industrial clusters generally face problems such as homogeneous layout, insufficient independent innovation capacity, low efficiency of industrial chain collaboration, lagging digital transformation of small and medium-sized enterprises, and imperfect brand and public service systems, which restrict the process of high-quality development. Empowering cluster division of labor and collaboration, innovation transformation, resource allocation and brand building with digital technologies, promoting the dual-wheel drive of institutional innovation and technological innovation, strengthening the leadership of leading enterprises and the integration of large, medium and small enterprises, and improving cluster public services and digital governance platforms can effectively realize the in-depth synergy between cluster-based development and high-quality development. This will help the industry climb to the high end of the global value chain and enhance the resilience and international competitiveness of the industrial and supply chains.